🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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Trial Search

Current Search Criteria:

Intervention: SoC (chemotherapy and platinum agent)

Found 23 matching trials

A Single-center Phase II Study to Investigate the Immune Maintenance Therapy Pattern in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Achieved MPR After Neoadjuvant Immunotherapy Combined With Chemotherapy

PHASE2

Head and neck cancer is the malignant tumor with the highest morbidity and ...

Status

Recruiting

Location

Tianjin Medical University Cancer Institute and Hospital

Start Date

2023-09-01

Trial ID

NCT06208826

Treatments Being Tested

Toripalimab Radiation Therapy Cisplatin

Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).

PHASE3

This is a randomized, open-label, multi-center, global, Phase III study to ...

Status

Active Not Recruiting

Location

Research Site

Start Date

2017-06-01

Trial ID

NCT03164616

Treatments Being Tested

Durvalumab Tremelimumab Abraxane + carboplatin Gemcitabine + cisplatin Gemcitabine + carboplatin Pemetrexed + carboplatin Pemetrexed + cisplatin

Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)

PHASE3

This is a randomized, open-label, multi-center Phase III study to determine...

Status

Active Not Recruiting

Location

Research Site

Start Date

2017-01-02

Trial ID

NCT03003962

Treatments Being Tested

Durvalumab (MEDI4736)Paclitaxel + carboplatin Gemcitabine + cisplatin Gemcitabine + carboplatin Pemetrexed + cisplatin Pemetrexed + carboplatin

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

PHASE3

The main goals of this study are to learn about the safety of sacituzumab t...

Status

Recruiting

Location

University of Alabama at Birmingham ( Site 0006)

Start Date

2025-04-09

Trial ID

NCT06824467

Treatments Being Tested

Sacituzumab tirumotecan Bevacizumab H1 receptor antagonist H2 receptor antagonist Acetaminophen (or equivalent)Dexamethasone (or equivalent)Steroid mouthwash (dexamethasone or equivalent)

Phase III Open Label Study of MEDI 4736 With/Without Tremelimumab Versus Standard of Care (SOC) in Recurrent/Metastatic Head and Neck Cancer

PHASE3

This is a randomized, open-label, multi-center, 3-arm, global Phase III stu...

Status

Completed

Location

Research Site

Start Date

2015-10-15

Trial ID

NCT02551159

Treatments Being Tested

MEDI4736 Tremelimumab MEDI4736+Tremelimumab Cetuximab 5-fluorouracil (5FU)Cisplatin Carboplatin

First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients.

PHASE3

First-line immunotherapy-based standard of care and local ablative treatmen...

Status

Recruiting

Location

Institut de Radiothérapie du Sud de l'Oise

Start Date

2025-09-09

Trial ID

NCT06840782

Treatments Being Tested

Radical local treatment SoC-based immunotherapy (+/- chemotherapy)

Thymosin Alpha 1 Plus Maintenance Therapy With the Standard of Care (SoC) in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC), EGFR Wild Type

PHASE2

Thymosin alpha 1 plus maintenance therapy with the Standard of Care (SoC) c...

Status

Unknown

Location

Azienda Sanitaria Locale Frosinone

Start Date

2016-09

Trial ID

NCT02906150

Treatments Being Tested

Thymalfasin (Thymosin alpha 1, Ta1)SoC (chemotherapy and platinum agent)

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)

PHASE3

This is a randomized, open-label, multi-center, global, Phase III study to ...

Status

Active Not Recruiting

Location

Research Site

Start Date

2015-11-03

Trial ID

NCT02542293

Treatments Being Tested

Durvalumab +Tremelimumab Paclitaxel + carboplatin Gemcitabine + cisplatin Gemcitabine + carboplatin Pemetrexed + cisplatin Pemetrexed + carboplatin

Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC)

PHASE1

Background: Lung cancer is the leading cause of cancer-related death world...

Status

Suspended

Location

National Institutes of Health Clinical Center

Start Date

2026-09-02

Trial ID

NCT06694454

Treatments Being Tested

azacytidine carboplatin paclitaxel durvalumab cisplatin gemcitabine pemetrexed

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

EARLY_PHASE1

This clinical trial evaluates the effects a probiotic intervention has on t...

Status

Recruiting

Location

Ohio State University Comprehensive Cancer Center

Start Date

2026-03-06

Trial ID

NCT07144826

Treatments Being Tested

Biospecimen Collection Placebo Administration Probiotic Questionnaire Administration

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